Program

8:30am – 9:00am – Registration

9:00am – 10:00am – Plenary Lecture 
Dopamine Dynamics
Ann Graybiel, MIT McGovern Institute

10:00am – 10:30am – Coffee Break

10:30am – 12:20pm – Parallel Sessions 1 – 5

Parallel Session 1, Basal Ganglia Integration of Motivation, Reward, and Drug-Seeking

Parallel Session 2, Neuro-immune mechanisms involved in Parkinson’s disease

Parallel Session 3, Dopamine-glial interactions contribute to normal and pathological behaviors

Parallel Session 4, Sensitivity of the corticolimbic dopamine (DA) system during development and maturation of neural circuits

Parallel Session 5, Emerging Striatal Dopamine Circuits in Threat Processing and Avoidance Learning

12:20pm – 2:15pm – Lunch / Poster Session 1

2:15pm – 4:00pm – Parallel Sessions 6 – 10

Parallel Session 6, How Addictive Substances Skew Dopamine–Acetylcholine Dynamics in the Striatum to Drive Compulsive Consumption

Parallel Session 7, Converging RNA biology and dopamine neuron vulnerability in Parkinson’s disease

Parallel Session 8, Dopamine in prediction, action, and control: Unravelling dopamine diversity across time and anatomical space

Parallel Session 9, Dopamine-acetylcholine interactions in striatum

Parallel Session 10, Beyond reward: decoding dopamine dynamics in amygdala circuits

4:00pm – 4:30pm – Coffee Break

4:30pm – 5:30pm – Plenary Lecture 
Spying on Neuromodulator Dynamics In Vivo by Constructing Multi-Color GRAB Sensors
Yulong Li, Peking University

6:00pm – 7:00pm – Public Lecture
Sociedad Andaluza de Neurología/Fundación Andaluza Parkinson (Spanish)

9:00am – 10:00am – Plenary Lecture
Dopamine signaling in isogenic mouse populations predicting addiction vulnerability
Christian Lüscher. University of Geneva, Switzerland

10:00am – 10:30am – Coffee Break

10:30am – 12:20pm – Parallel Sessions 11 – 15

Parallel Session 11, Dopamine and behavioral control: from action selection to persistence and effort

Parallel Session 12, From Rodents to Humans: Exploring Neuromelanin’s Role in Parkinson’s Disease

Parallel Session 13, Revisiting sex differences in the regulation of dopamine release to uncover novel mechanisms of motivated behaviors

Parallel Session 14, Here be dragons: Mapping the uncharted territories of dopamine topology

Parallel Session 15, Dopamine and Schizophrenia: Translational Approaches from mice to humans

12:20pm – 2:15pm – Lunch / Poster Session 2

2:15pm – 4:00pm – Parallel Sessions 16 – 20

Parallel Session 16, Motivational decision-making, exertion of effort, and regulation of physical activity: cortical and subcortical dopamine mechanisms

Parallel Session 17, Functional diversity as a design principle: From molecular and anatomical heterogeneity to circuit flexibility

Parallel Session 18, Bridging Metabolism and Motivation: The Central Role of Insulin

Parallel Session 19, Computational Efforts to Explain Dopamine Dynamics Throughout the Striatum

Parallel Session 20, Dopamine circuit plasticity mechanisms in reward-free motor learning

4:00pm – 4:30pm – Coffee Break

4:30pm – 5:30pm – Plenary Lecture
New Drugs, Old Targets: Tweaking the Dopamine System to Treat Substance Use Disorders
Amy Newman, National Institutes of Health

6:00pm – 8:00pm – Social Activity, Flamenco & City Tour

9:00am – 10:00am – Plenary Lecture
Nucleus accumbens and the architecture of associative learning: from simple cues to complex associative chains
Ana Joao Rodrigues, University of Minho

10:00am – 10:30am – Coffee Break

10:30am – 12:20pm – Parallel Sessions 21 – 25

Parallel Session 21, The role of dopaminergic systems in associating and integrating world information to motivate actions

Parallel Session 22, Glia and matrix in PD and dopaminer transmission

Parallel Session 23,Dopamine’s Role in the Hippocampal Formation: From Novelty to Associative and Spatial Memories

Parallel Session 24, DATs all folks: dynamic regulation and functional importance of dopamine transporters in physiological and pathophysiological states

Parallel Session 25, Dopamine and Individuality: Inter-individual Variability, Specialization, and Social Context in Adaptive and Maladaptive Behaviors

12:20pm – 2:15pm – Lunch / Poster Session 3

2:15pm – 4:00pm – Parallel Sessions 26 – 30

Parallel Session 26, Integrative roles of dopamine in sensory and emotional processing

Parallel Session 27, Dopamine vs noradrenaline contributions to non-motor features of Parkinson’s disease: From animal models to clinicopathology

Parallel Session 28, Novel sensors, technologies, and assays for measuring dopamine

Parallel Session 29, Metabolic signals and dopamine transmission

Parallel Session 30, Cues, craving, and consequences: How drug and reward signals shape appetitive behaviour

4:00pm – 4:30pm – Coffee Break

5:00pm – 6:00pm – Debate

Mitochondrial dysfunction is a common determinant of neurodegeneration in Parkinson’s disease
James Surmeier, Northwestern University

Progressive Parkinson’s disease requires α-synuclein aggregation
Michael Henderson, Van Andel Institute

6:00pm – 6:45pm – Business Meeting

9:00am – 10:00am – Plenary Lecture
Running on Dopamine: Exercise, Motor Behavior, and Striatal Plasticity
Margaret Rice, New York University

10:00am – 10:30am – Coffee Break

10:30am – 12:20pm – Parallel Sessions 31 – 35

Parallel Session 31, A fork in – or the end of – the road? Challenges to classic RL models of dopamine function and where we might go from here

Parallel Session 32, Biomarkers and cognitive implications of aging-related dopamine decline

Parallel Session 33, The architecture of dopaminergic neurons: from molecular organization to behavior and disease

Parallel Session 34, Dopamine dysregulated: the cortico-basal ganglia network in hypokinesia and dyskinesia

Parallel Session 35, Omics Approaches and Cellular Reprogramming in Parkinson’s Disease

12:20pm – 2:15pm – Lunch / Poster Session 4

2:15pm – 4:00pm – Parallel Sessions 36 – 41

Parallel Session 36, Dopamine neuron subtype-specific circuit development and repair

Parallel Session 37, Prediction errors beyond reward: dopamine shaping perceptual decisions

Parallel Session 38, Dopaminergic neuron diversity in the substantia nigra and its relevance for Parkinson’s disease

Parallel Session 39, Imaging dopamine, neuromelanin, and iron in the human brain: applications in neurodegenerative and psychiatric illness

Parallel Session 40, New Frontiers in Dopaminergic Signaling: Bidirectional Brain–Body Regulation in Neurological and Neuropsychiatric Disorders

Parallel Session 41, How Addicitve Substances Skew Dopamine 0 Acetylcholine Dynamics in the Striatum to Drive Compulsive Consumption

4:00pm – 4:30pm – Coffee Break

4:30pm – 5:30pm – Plenary Lecture
Distinct circuits for specific movements in the basal ganglia
Rui Costa, Allen Institute

5:30pm – 5:45pm – Closing Remarks

7:00pm – 10:00pm – Conference Dinner at an offsite location